Necrostatin-1

SKU
N-1227
  • CAS:4311-88-0
  • Formula:C13H13N3OS
  • MW:259.332
  • Appearance:Yellow Solid
  • Purity:98 (TLC)

0

0

0

0

Product Name Qty
Necrostatin-1
5 mg
$68.12
Necrostatin-1
25 mg
$276.96
Inhibits necroptosis, a non-apoptotic cell death pathway. Does not inhibit FAS-induced apoptosis and has no effect on apoptotic morphology. Inhibits RIP1 kinase, the key upstream kinase involved in the activation of necroptosis (EC = 180 nM)
More Information
Alternate Name/Synonyms
Nec-1
SKU
N-1227
CAS #
4311-88-0
Chemical Name
Methythiohydantoin-DL-tryptophan
Chemical Formula
C13H13N3OS
Molecular Weight
259.332
Appearance
Yellow Solid
Purity
98 (TLC)
Solubility
Soluble in DMSO (25mg/ml) or EtOH(6mg/ml)
Storage Temp
-20°C
THERAPEUTIC AREA
Neurological Disorders
USE
An inhibitor of the necroptosis cell death pathway used necroptosis in ischemic brain injury
MDL NUMBER
MFCD00056916
CHEMACX
X1093197-8
INCHI
InChI=1S/C13H13N3OS/c1-16-12(17)11(15-13(16)18)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,11,14H,6H2,1H3,(H,15,18)
SMILES
CN1C(=O)C(NC1=S)Cc2c[nH]c3c2cccc3
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and light
Certificate of Analysis 1
Certificate of Analysis 2
Certificate of Analysis 3
Handling Protect from air and light
UN #'S Not Applicable
Packing Group Not Applicable
To Top