SDS
CofA
A necroptosis inhibitor. The biological activity of necrostatin-7 (Nec 7) is different from that of necrostatin 1 to necrostatin 5 as Nec 7 does not inhibit RIP1 kinase. Nec-7 may target an additional regulatory molecule in the pathway.
More Information
Alternate Name/Synonyms
NEC-7, Necroptosis inhibitor 7
SKU
N-1225
CAS #
351062-08-3
Chemical Name
(Z)-5-((4-Fluorophenyl)-1H-pyazol-4-yl)methylene)-2-imino-3-(thiazol-2-yl)thiazolidin-4-one
Chemical Formula
C16H10N5OS2F
Molecular Weight
371.41
Appearance
Yellow Solid
Purity
98% by NMR
Solubility
Soluble in DMSO or EtOH.
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
Not Available
MDL NUMBER
MFCD02334728
CHEMACX
Not Applicable
INCHI
InChI=1S/C16H10FN5OS2/c17-11-3-1-9(2-4-11)13-10(8-20-21-13)7-12-14(23)22(15(18)25-12)16-19-5-6-24-16/h1-8,18H,(H,20,21)/b12-7+,18-15?
SMILES
c1cc(ccc1c2c(c[nH]n2)/C=C/3C(=O)N(C(=N)S3)c4nccs4)F
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from moisture. Wear gloves and mask when handling this product.
Certificate of Analysis 1
| GHS PICTOGRAMS |  |
|---|---|
| Handling | Protect from moisture. Wear gloves and mask when handling this product. |
| UN #'S | Not Applicable |
| Packing Group | Not Applicable |
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