Netropsin Dihydrochloride

SKU
N-4000
  • CAS:18133-22-7
  • Formula:C18H26N10O3•2HCl
  • MW:503.39 Da
  • Appearance:Off-white powder
  • Purity:>98% by HPLC

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Product Name Qty
Netropsin Dihydrochloride
25 mg
$175.00
Netropsin Dihydrochloride
50 mg
$349.99
Netropsin Dihydrochloride
5 mg
$39.99
Netropsin Dihydrochloride
10 mg
$75.00

Description

Isolated from Streptomyces netropsis, Netropsin Dihydrochloride is a DNA minor groove binding ligand that shows potential antibiotic and antiviral properties. Netropsin Dihydrochloride displays a strong affinity for the AT-rich region in double-stranded DNA, acting as a binding ligand to nucleic acid. Netropsin has been reported to bind to double-stranded DNA at specific base sequences and can block DNA helicase, topoisomerase, and endonuclease. It has also been reported to interfere with transcription factor binding. Netropsin Dihydrochloride binds to double-stranded DNA in a non-intercalative manner when used as an antibiotic.

 

More Information
Alternate Name/Synonyms
Congocidin, Sinanomycin
SKU
N-4000
CAS #
18133-22-7
Chemical Formula
C18H26N10O3•2HCl
Molecular Weight
503.39 Da
Appearance
Off-white powder
Purity
>98% by HPLC
Solubility
Methanol: clear colorless solution at 10 mg/mL
Melting Point
242-245°C
USE
DNA minor groove binding ligand, potential antibiotic and antiviral properties
INCHI
SDRHUASONSRLFR-UHFFFAOYSA-N
GHS PICTOGRAMS
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