- MW:503.39 Da
- Appearance:Off-white powder
- Purity:≥98% by HPLC
Isolated from Streptomyces netropsis, Netropsin Dihydrochloride is a DNA minor groove binding ligand that shows potential antibiotic and antiviral properties. Netropsin Dihydrochloride displays a strong affinity for the AT-rich region in double-stranded DNA, acting as a binding ligand to nucleic acid. Netropsin has been reported to bind to double-stranded DNA at specific base sequences and can block DNA helicase, topoisomerase, and endonuclease. It has also been reported to interfere with transcription factor binding. Netropsin Dihydrochloride binds to double-stranded DNA in a non-intercalative manner when used as an antibiotic.
• EU Number: 634-294-2
|Handling||Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed.|