Nonactin is a cyclic ionophore that belongs to the macrotetrolide antibiotic family. The process of nonactin is to bind a metal ion and transport it across the cell membrane. This is possible due to the compounds conformational flexibility and hydrophobic exterior. Nonactin also inhibits the processing of cytoplasmic precursor proteins destined for the mitochondria.
• Used to inhibit the production of gene transcription
• Used to facilitate the movement of monovalent cations through natural and artificial membranes
• Used as an ammonium ionophore for ammonium ion determination in a potentiometric electrode for biosensor construction
Not for human therapeutic use or for medicinal purposes. For research applications only.
|Handling||Use only in area provided with appropriate exhaust ventilation. Keep away from heat and source of ignition. Empty containers pose a fire risk, evaporate residue under fume hood. Ground all equipment containing material. Do not breathe dust.|