Werramycin-A; Ammonium ionophore; Ammonium ionophore I; Macrotetrolide analogue
6833-84-7
736.93
C40H64O12
Dichloromethane, DMSO
-20°C
Nonactin is a cyclic ionophore that belongs to the macrotetrolide antibiotic family. The process of nonactin is to bind a metal ion and transport it across the cell membrane. This is possible due to the compounds conformational flexibility and hydrophobic exterior. Nonactin also inhibits the processing of cytoplasmic precursor proteins destined for the mitochondria.
Applications:
- Used to inhibit the production of gene transcription
- Used to facilitate the movement of monovalent cations through natural and artificial membranes
- Used as an ammonium ionophore for ammonium ion determination in a potentiometric electrode for biosensor construction
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
