NSC-23766

SKU
N-1217
  • CAS:733767-34-5
  • Formula:C24H35N7.3HCl
  • MW:530.97
  • Appearance:White Solid
  • Purity:98%

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Product Name Qty
NSC-23766
1 mg
$72.59
A cell-permeable, reversible, and selective Rac1 inhibitor; inhibiting Rac1 activation by the Rac-specific guanine nucleotide exchange factors (GEFs) TrioN an Tiam 1 without affecting the closely related GTPases, Cdc42, and RhoA activation. NSC 23766 has been used to investigate the role of Rac1 in such diverse cellular functions as stem cell mobilization, epithelial cell migration, angiogenesis, leukemia cell migration and growth
More Information
Alternate Name/Synonyms
RAC 1 INHIBITOR
SKU
N-1217
CAS #
733767-34-5
Chemical Name
6-N-[2-[5-(DIETHYLAMINO)PENTAN-2-YLAMINO]-6-METHYLPYRIMIDIN-4-YL]-2-METHYLQUINOLINE-4,6-DIAMINE TRIHYDROCHLORIDE
Chemical Formula
C24H35N7.3HCl
Molecular Weight
530.97
Appearance
White Solid
Purity
98%
Solubility
Soluble in water (100mM).
Stability
N/A
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
The inhibition of NSC23766 on cell cycle arrest or apoptosis in breast cancer
MDL NUMBER
MFCD08703096
CHEMACX
X1579306-5
INCHI
InChI=1S/C24H35N7.3ClH/c1-6-31(7-2)12-8-9-16(3)27-24-28-18(5)14-23(30-24)29-19-10-11-22-20(15-19)21(25)13-17(4)26-22;;;/h10-11,13-16H,6-9,12H2,1-5H3,(H2,25,26)(H2,27,28,29,30);3*1H
SMILES
CCN(CC)CCCC(C)Nc1nc(cc(n1)Nc2ccc3c(c2)c(cc(n3)C)N)C.Cl.Cl.Cl
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Hygroscopic. Protect from moisture. Do not take internally. Wear gloves and mask when handling the product.Avoid contact by all modes of exposure.
Certificate of Analysis 1
Promo text for AGS discount
N/A
GHS PICTOGRAMS
Handling Hygroscopic. Protect from moisture. Do not take internally. Wear gloves and mask when handling the product.Avoid contact by all modes of exposure.
UN #'S Not Applicable
Packing Group Not Applicable
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