SDS
CofA
p53/mdm2 inhibitor
More Information
SKU
N-2587
CAS #
6964-62-1
Chemical Formula
C23 H20 N2 O
Molecular Weight
340.424
Appearance
Solid
Solubility
DMSO (100mM)
Storage Temp
+4°C
THERAPEUTIC AREA
Oncological Disorders
USE
NSC 66811 is a potent MDM2 inhibitor which disrupts MDM2-p53 interaction and activates p53 function. Induces p21, p53 and MDM2 accumulation in human colon cancer cells
MDL NUMBER
MFCD08823776
CHEMACX
X1763940-4
INCHI
InChI=1S/C23H20N2O/c1-16-12-13-18-14-15-20(23(26)22(18)24-16)21(17-8-4-2-5-9-17)25-19-10-6-3-7-11-19/h2-15,21,25-26H,1H3
SMILES
Cc1ccc2ccc(c(c2n1)O)C(c3ccccc3)Nc4ccccc4