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NVP-AUY922

SKU
N-2368
  • CAS:747412-49-3
  • Formula:C26H31N3O6
  • MW:465.54
  • Appearance:White to off-white Solid
  • Purity:99%
Product Name Qty
NVP-AUY922
1 mg
$336.03
NVP-AUY922
5 mg
$1,019.47
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A Hsp90 inhibitor. NVP-AUY922 has excellent potency against Hsp90 in a fluorescence polarization binding assay with an ICof 21 nmol/L against theisoform and of 13 nmol/L for the isoform.

More Information
Alternate Name/Synonyms
5-(2,4-Dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
SKU
N-2368
CAS #
747412-49-3
Chemical Name
5-(2,4-Dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
Chemical Formula
C26H31N3O6
Molecular Weight
465.54
Appearance
White to off-white Solid
Purity
99%
Solubility
DMSO (10 mM)
Melting Point
178-190 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
A highly potent HSP90 inhibitor to HSP90α and HSP90β in cancer
MDL NUMBER
MFCD14635361
CHEMACX
X1812371-2
INCHI
InChI=1S/C26H31N3O5/c1-4-27-26(32)24-23(18-7-5-17(6-8-18)15-29-9-11-33-12-10-29)25(34-28-24)20-13-19(16(2)3)21(30)14-22(20)31/h5-8,13-14,16,30-31H,4,9-12,15H2,1-3H3,(H,27,32)
SMILES
CCNC(=O)c1c(c(on1)c2cc(c(cc2O)O)C(C)C)c3ccc(cc3)CN4CCOCC4
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light and moisture
GHS PICTOGRAMS
Handling Protect from light and moisture
UN #'S Not Applicable
Packing Group Not Applicable
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