Olaparib

SKU
O-2371
  • CAS:763113-22-0
  • Formula:C24H23FN4O3
  • MW:434.46
  • Appearance:White to off-white Solid
  • Purity:98% by HPLC
Product Name Qty
Olaparib
5 mg
$83.75
Olaparib
25 mg
$318.27
Cell-permeable. A highly potent and selective PARP-inhibitor with ICvalues of 5 nM and 1 nM for PARP-1 and PARP-2, respectively. Olaparib displays standalone activity in BRCA-1 deficient breast cancer cells.
More Information
Alternate Name/Synonyms
ADZ-2281; KU-59436
SKU
O-2371
CAS #
763113-22-0
Chemical Name
4-(3-(4-(cycloprppanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazine-1(2H)-one; ADZ-2281; KU-59436
Chemical Formula
C24H23FN4O3
Molecular Weight
434.46
Appearance
White to off-white Solid
Purity
98% by HPLC
Solubility
DMSO (~33 mg/ml) or EtOH (~ 1.7 mg/ml)
Stability
N/A
Melting Point
157-170 ºC
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
A potent inhibitor of PARP use in cancer
MDL NUMBER
MFCD13185161
CHEMACX
X1812343-8
INCHI
InChI=1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26-21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13,16H,6-7,9-12,14H2,(H,27,30)
SMILES
c1ccc2c(c1)c(n[nH]c2=O)Cc3ccc(c(c3)C(=O)N4CCN(CC4)C(=O)C5CC5)F
Handling
Protect from light and air
E-Guides
N/A
Blog Post
N/A
Certificate of Analysis 1
Promo text for AGS discount
N/A
GHS PICTOGRAMS
Handling Protect from light and air
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