- MW:775.1 Da
- Appearance:White Lyophilisate
- Purity:≥95% by HPLC
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Oligomycin C is part of a class of macrolide antibiotics and is a potent inhibitor of cell regulatory volume decrease (RVD). Oligomycin has been shown to inhibit ATP synthase by blocking the ATP5 (mitochondrial F1F0-ATPase).
Doxorubicin-resistant HepG2 cell studies report that oligomycin can inhibit the activity of P-glycoprotein and induce apoptosis.
Isolated from Streptomyces sp.
Not for human therapeutic use or for medicinal purposes. For research applications only.
|Handling||Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product.|