- MW:777.0 Da
- Appearance:White Lyophilisate
- Purity:>95% by HPLC
INQUIRE FOR PRICING & AVAILABILITY
Oligomycin D (rutamycin) is macrocyclic lactone belonging to the oligomycin class but identified from different species of Streptomyces in 1961. Like oligomycin A, oligomycin D inhibits mitochondrial F1F0-ATPase and is an important bioprobe to study the organisation of ATPase on the mitochondrial membrane.
Oligomycin D exhibits a broad biological profile including antifungal, antitumor and nematocidal activities.
Isolated from Streptomyces sp.
• Antifungal antibiotic rutamycin and process for the production thereof. Thompson R.Q. US Patent 3,310,468,
• Assembly of the mitochondrial system. Purification of a mitochondrial product of the ATPase. Sierra M.F. &
Tzagoloff A. Proc. Natl. Acad. Sci. U.S.A. 1973, 70, 3155.
Not for human therapeutic use or for medicinal purposes. For research applications only.
|Handling||Handle in accordance with good industrial hygiene and safety practice.|