Oligomycin E

SKU
O-2549
  • CAS:110231-34-0
  • Formula:C45H72O13
  • MW:821.1 Da
  • Appearance:White Lyophilisate
  • Purity:>95% by HPLC
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Description

Oligomycin E (26-hydroxyoligomycin B) is a minor metabolite from the oligomycin complex produced by several species of Streptomyces.

Unlike the other oligomycins, oligomycin E exhibits weak antibacterial activity and is considerably weaker as an antifungal agent.

References

Oligomycin E, a new antitumor antibiotic produced by Streptomyces sp. MCI-2225. Kobayashi K. et al., J.
Antibiot. 1987, 40, 1053.

Not for human therapeutic use or for medicinal purposes. For research applications only.

More Information
Alternate Name/Synonyms
26-hydroxy-28-oxooligomycin A
SKU
O-2549
CAS #
110231-34-0
Chemical Name
(1R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,27S,28R,29R)-22-ethyl-7,11,14,15,28-pentahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethylspiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-oxane]-3,3',9,13-tet
Chemical Formula
C45H72O13
Molecular Weight
821.1 Da
Appearance
White Lyophilisate
Purity
>95% by HPLC
Solubility
Soluble in ethanol, methanol, DMF, or DMSO. Limited water solubility.
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
A minor metabolite from the oligomycin complex with weak antibacterial and antifungal activity
INCHI
InChI=1S/C45H72O13/c1-12-32-17-15-13-14-16-25(3)40(52)43(10,54)41(53)31(9)39(51)30(8)38(50)29(7)37(49)24(2)18-21-36(48)56-42-28(6)33(20-19-32)57-45(44(42,11)55)35(47)22-26(4)34(58-45)23-27(5)46/h13-15,17-18,21,24-34,37,39-40,42,46,49,51-52,54-55H,12,16,19-20,22-23H2,1-11H3/b14-13-,17-15-,21-18+
SMILES
CCC\1CCC2C(C(C(C3(O2)C(=O)CC(C(O3)CC(C)O)C)(C)O)OC(=O)/C=C/C(C(C(C(=O)C(C(C(C(=O)C(C(C(C/C=C\C=C1)C)O)(C)O)C)O)C)C)O)C)C
Handling
Handle in accordance with good industrial hygiene and safety practice.
Handling Handle in accordance with good industrial hygiene and safety practice.
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