- Appearance:White solid
- Purity:>98% by HPLC
*Please inquire the availability for this product. Orfamide A is the major component of a family of cyclic lipopeptides produced by Pseudomonas fluorescens, reported in 2007. The orfamides were discovered by employing genomic analysis with an isotope-guided fractionation to identify metabolites produced by orphan gene clusters containing non-ribosomal peptide synthetases. Orfamide A has received scant investigation of its bioprofile but appears to be a selective antifungal agent. Uniquely, orfamide A lyses zoospores of the oomycete, Phytophthora ramorum, the cause of sudden oak death. Orfamide A has a profound effect on the swarming motility of bacteria on agar surfaces.
>98% by HPLC
Soluble in ethanol, methanol, DMF or DMSO Poor water solubility
Orfamide A appears to be a selective antifungal agent