- Appearance:White solid
- Purity:>99% by HPLC
*Please inquire the availability for this product. Ostreogrycin A (virginiamycin M1, streptogramin A) is the major component of the virginiamycin complex. In the 1950s this complex was independently discovered so many times that the literature became highly confusing. Ostreogrycin A is a macrocyclic lactone antibiotic that acts synergistically with the structurally unrelated cyclic depsipeptides, virginiamycin B (ostreogrycin B, streptogramin B) and virginiamycin S, to inhibit peptide elongation. This is achieved by blocking formation of a peptide bond between the growing peptide chain (peptidyl-tRNA) linked to the 50S ribosome and aminoacyl-tRNA. Ostreogrycin A is highly active against Gram positive bacteria, particularly MRSA.
Mikamycin A, Pristinamycin IIA, Stephylomycin M1, Streptogramin A, Syncothrecin A, Synergistin A1, Virginiamycin M1, Vernamycin A, 14752-2, E129A, PA 114A, 1745Z3A, 547C, Factor M
>99% by HPLC
Soluble in water (partly), ethanol (4%), methanol (4%), DMF, and DMSO
Ostreogrycin A has highly active against Gram positive bacteria