Paclitaxel (Taxol), Taxus brevifolia

SKU
P-1027
  • CAS:33069-62-4
  • Formula:C47H51NO14
  • MW:853.9
  • Appearance:White Crystalline Powder
  • Purity:98%
Product Name Qty
Paclitaxel (Taxol), Taxus brevifolia
5 mg
$39.08
Paclitaxel (Taxol), Taxus brevifolia
25 mg
$61.42
Paclitaxel (Taxol), Taxus brevifolia
100 mg
$206.60

Anti-tumor agent isolated from the bark of the yew tree.Attached is a published reference from researchers who have used our paclitaxel product.Tectorigenin sensitizes paclitaxel-resistant human ovarian cancer cells through downregulation of the Akt and NFB pathway.Weekly paclitaxel has limited activity in esophageal cancer. The median survival, modest activity, and tolerance of therapy indicate that weekly paclitaxel may be an option in patients unable to tolerate combination chemotherapy. .Paclitaxel Enhances TF Protein Expression and Surface Activity.Paclitaxel Enhances Thrombin-Induced Endothelial Tissue Factor Expression via c-Jun Terminal NH.

More Information
Alternate Name/Synonyms
Taxol, Baccatin III N-benzyl-phenylisoserine ester
SKU
P-1027
CAS #
33069-62-4
Chemical Name
Baccatin III N-benzyl-β-phenylisoserine ester
Chemical Formula
C47H51NO14
Molecular Weight
853.9
Appearance
White Crystalline Powder
Purity
98%
Solubility
DMSO
Storage Temp
-20°C. PROTECT FROM LIGHT! WARNING: TOXIC! IRRITANT!
THERAPEUTIC AREA
Oncological Disorders
USE
An antineoplastic and apoptosis inducing agent
Merck Index
12.7117.1996
MDL NUMBER
MFCD00869953
CHEMACX
X1009807-6
INCHI
InChI=1S/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33-46(38,24-58-33)62-27(3)50)39(53)37(59-26(2)49)34(25)44(47,4)5/h7-21,31-33,35-38,40,51-52,57H,22-24H2,1-6H3,(H,48,54)/t31-,32-,33+,35-,36+,37+,38-,40-,45+,46-,47+/m0/s1
SMILES
CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](c5ccccc5)NC(=O)c6ccccc6)O)O)OC(=O)c7ccccc7)(CO4)OC(=O)C)O)C)OC(=O)C
RTECS
DA8340700
Handling
Warning.Toxic. May be Carcinogenic. Wear gloves/mask when handling product. Avoid contact by all means of exposure.
Certificate of Analysis 1
Certificate of Analysis 2
Certificate of Analysis 3
Handling Warning.Toxic. May be Carcinogenic. Wear gloves/mask when handling product. Avoid contact by all means of exposure.
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