- Appearance:Crystalline Solid
- Purity:99% by HPLC
Panobinostat (LBH589) is a highly potent inhibitor of both histone deacetylase 1 (HDAC1) activity and tumour cell proliferation in vitro. The ICvalues of HDAC isozymes HDAC1-IP Ac-H4, HDAC8, MALunselective, B61HDAC1 and B12HDAC6 are 0.230.06, 28329, 754, 475 and 8912 nM, respectively. And to A2780 proliferation, ICvalue is 4.61.8 nM.
|Handling||Protect from air and moisture|