Paraherquamide A, Penicillium simlicissimum

SKU
P-1470
  • CAS:77392-58-6
  • Formula:C28H35N3O5
  • MW:493.6
  • Appearance:White Powder
  • Purity:95% by HPLC
Product Name Qty
Paraherquamide A, Penicillium simlicissimum
5 mg
$1,121.98
Paraherquamide A, Penicillium simlicissimum
1 mg
$405.51

Paraherquamide A was first reported as a mycotoxin related to the indole tremorgenic mycotoxins. Subsequent research identified a potent non-toxic paralysis of nematodes which led to the metabolite's development as a candidate anthelmintic. Paraherquamide A is a selective, competitive, cholinergic antagonist that distinguishes subtypes of cholinergic receptors.

More Information
Alternate Name/Synonyms
Antibiotic VM 29919
SKU
P-1470
CAS #
77392-58-6
Chemical Name
(1R,3S,5R,7S,12R)-12-HYDROXY-4,4,4',4',12,14-HEXAMETHYL-4'H,13H-SPIRO[9,14-DIAZATETRACYCLO[5.5.2.01,9.03,7]TETRADECANE-5,8'-[1,4]DIOXEPINO[2,3-G]INDOLE]-9',13(10'H)-DIONE
Chemical Formula
C28H35N3O5
Molecular Weight
493.6
Appearance
White Powder
Purity
95% by HPLC
Solubility
Soluble in ethanol, methanol, DMF or DMSO
Melting Point
290.08 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
Paraherquamide A was first reported as a mycotoxin related to the indole tremorgenic mycotoxins
MDL NUMBER
MFCD01709427
CHEMACX
X3299411-3
INCHI
InChI=1S/C28H35N3O5/c1-23(2)10-12-35-20-17(36-23)8-7-16-19(20)29-21(32)27(16)14-26-15-31-11-9-25(5,34)28(31,22(33)30(26)6)13-18(26)24(27,3)4/h7-8,10,12,18,34H,9,11,13-15H2,1-6H3,(H,29,32)/t18-,25+,26+,27+,28-/m0/s1
SMILES
C[C@]1(CCN2[C@]13C[C@@H]4[C@](C2)(C[C@@]5(C4(C)C)c6ccc7c(c6NC5=O)OC=CC(O7)(C)C)N(C3=O)C)O
Peptide sequence
Not Applicable
RTECS
RV0545000
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Certificate of Analysis 1
UN #'S Not Applicable
Packing Group Not Applicable
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