Paraherquamide E, Penicillium sp.

SKU
P-1471
  • CAS:125600-53-5
  • Formula:C28H35N3O4
  • MW:477.6
  • Appearance:White solid
  • Purity:> 99% by HPLC
Product Name Qty
Paraherquamide E, Penicillium sp.
500 ug
$405.51

Paraherquamide E is a member of the paraherquamide family which cause a potent non-toxic paralysis of nematodes and has led to investigation of their potential as anthelmintics. Although paraherquamide A has received more attention, paraherquamide E has been shown to be the more potent anthelmintic in vivo. Paraherquamide E was also found to be the most potent insecticide in a series of paraherquamide analogues against a hemipteran with an LD50 of 0.089 ug/nymph.Recently purified metabolite.

More Information
Alternate Name/Synonyms
Antibiotic VM 54159, 14-Deoxy-paraherquamide A
SKU
P-1471
CAS #
125600-53-5
Chemical Formula
C28H35N3O4
Molecular Weight
477.6
Appearance
White solid
Purity
> 99% by HPLC
Solubility
Soluble in ethanol, methanol, DMF or DMSO
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
Paraherquamide E is the more potent anthelmintic
MDL NUMBER
MFCD08062313
INCHI
InChI=1S/C28H35N3O4/c1-16-9-11-31-15-26-14-27(25(4,5)19(26)13-28(16,31)23(33)30(26)6)17-7-8-18-21(20(17)29-22(27)32)34-12-10-24(2,3)35-18/h7-8,10,12,16,19H,9,11,13-15H2,1-6H3,(H,29,32)/t16-,19-,26+,27+,28+/m0/s1
SMILES
O=C2Nc1c7O\C=C/C(Oc7ccc1[C@]26C[C@@]45N(C(=O)[C@@]3(N(CC[C@@H]3C)C4)C[C@H]5C6(C)C)C)(C)C
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