PC-766B

SKU
P-2747
  • CAS:108375-77-5
  • Formula:C43H68O12
  • MW:777
  • Appearance:Light orange solid
  • Purity:>95% by HPLC
Product Name Qty
PC-766B
1 mg
$293.64
PC-766B
5 mg
$1,027.76
*Please inquire the availability for this product. PC-766B is a 16-membered macrolide antibiotic produced by Nocardia brasiliensis, reported by researchers at Sumitomo in 1993. Structurally, PC-766B is a member of bafilomycin class, featuring a rare butadiene side-chain. PC-766B is active against Gram positive bacteria, and some fungi and yeasts, but is inactive against Gram negative bacteria. It shows activity against murine tumor cells in vitro and in vivo, and weak inhibitory activity against Na/K-ATPase in vitro.
More Information
SKU
P-2747
CAS #
108375-77-5
Chemical Formula
C43H68O12
Molecular Weight
777
Appearance
Light orange solid
Purity
>95% by HPLC
Solubility
Soluble in ethanol, methanol, DMF or DMSO
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
An antibiotic with activity against gram positive bacteria and some fungi and yeasts
INCHI
InChI=1S/C43H68O12/c1-12-13-14-17-33-28(6)36(53-37-22-32(44)40(47)31(9)52-37)23-43(49,55-33)30(8)39(46)29(7)41-34(50-10)18-15-16-24(2)19-26(4)38(45)27(5)20-25(3)21-35(51-11)42(48)54-41/h12-18,20-21,26-34,36-41,44-47,49H,19,22-23H2,1-11H3/b13-12+,17-14+,18-15-,24-16-,25-20-,35-21-/t26-,27+,28+,29?,30-,31+,32+,33+,34-,36+,37+,38-,39+,40+,41+,43+/m0/s1
SMILES
C/C=C/C=C/[C@@H]1[C@H]([C@@H](C[C@@](O1)([C@@H](C)[C@@H](C(C)[C@@H]2[C@H](/C=C\C=C(/C[C@@H]([C@@H]([C@@H](/C=C(\C=C(\C(=O)O2)/OC)/C)C)O)C)\C)OC)O)O)O[C@@H]3C[C@H]([C@@H]([C@H](O3)C)O)O)C
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