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PD 158780

SKU
P-1649
  • CAS:171179-06-9
  • Formula:C14H12BrN5
  • MW:330.2
  • Appearance:Yellow Solid
  • Purity:95%
Product Name Qty
PD 158780
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A potent inhibitor of the EGFR tyrosine kinase activity (IC=8pM). Also inhibits heregulin-stimulated autophosphorylation in SK-BR-3 (IC=49nM)and MDA-MB-453 (IC=52 nM)breast carcinomas.
More Information
Alternate Name/Synonyms
4-[(3-Bromophenyl)amino]-6-(methylamino)-pyrido[3,4-d]pyridimine
SKU
P-1649
CAS #
171179-06-9
Chemical Name
4-[(3-Bromophenyl)amino]-6-(methylamino)-pyrido[3,4-d]pyridimine
Chemical Formula
C14H12BrN5
Molecular Weight
330.2
Appearance
Yellow Solid
Purity
95%
Solubility
Soluble in DMSO
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Inhibits heregulin-stimulated autophosphorylation in SK-BR-3 and MDA-MB-453 in breast carcinomas.
MDL NUMBER
MFCD00942160
CHEMACX
X1535395-4
INCHI
InChI=1S/C14H12BrN5/c1-16-13-6-11-12(7-17-13)18-8-19-14(11)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20)
SMILES
CNc1cc2c(cn1)ncnc2Nc3cccc(c3)Br
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from Light Packaged under inert gas.
Handling Protect from Light Packaged under inert gas.
UN #'S Not Applicable
Packing Group Not Applicable
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