PD 168393

SKU
P-1653
  • Formula:C17H13BrN4O
  • MW:369.2
  • Appearance:Orange-yellow Solid
  • Purity:95%
Product Name Qty
PD 168393
1 mg
$240.10
A potent, cell-permeable, irreversible, and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (IC=0.70 nM. Does not inhibit other protein kinases. Acts by binding to the catalytic domain of the EGFR with a 1:1 stoichiometry and alkylating Cys. Excellent antitumor agent in vivo.
More Information
Alternate Name/Synonyms
4-[(3-Bromophenyl)amino]-6-acrylamidoquinazoline
SKU
P-1653
Chemical Name
4-[(3-Bromophenyl)amino]-6-acrylamidoquinazoline
Chemical Formula
C17H13BrN4O
Molecular Weight
369.2
Appearance
Orange-yellow Solid
Purity
95%
Solubility
Soluble in DMSO
Stability
N/A
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Epidermal growth factor receptor inhibitor (PD168393) potentiates cytotoxic effects of paclitaxel against androgen-independent prostate cancer
MDL NUMBER
MFCD02179207
CHEMACX
X1498384-9
PubChecm ID
N/A
INCHI
InChI=1S/C17H13BrN4O/c1-2-16(23)21-13-6-7-15-14(9-13)17(20-10-19-15)22-12-5-3-4-11(18)8-12/h2-10H,1H2,(H,21,23)(H,19,20,22)
SMILES
C=CC(=O)Nc1ccc2c(c1)c(ncn2)Nc3cccc(c3)Br
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from Light Packaged under inert gas.
Special Shipping
N/A
E-Guides
N/A
Blog Post
N/A
Citations
N/A
Citations_Hyperlink
N/A
Reference
N/A
Reference Hyperlink
N/A
Additional Images
N/A
Additional Videos
N/A
Hazard Image
N/A
Structure Available (Y/N)
N/A
Promo text for AGS discount
N/A
Handling Protect from Light Packaged under inert gas.
UN #'S Not Applicable
Packing Group Not Applicable
To Top