- Appearance:Crystalline Solid
- Purity:98% by TLC
A potent and selective FGFR1 tyrosine kinase inhibitor (IC= 21.5 nM). Blocking of the FGFR signaling pathway by PD 173074 leads to self-renewal of stem cells via ERK1/2 activation. Treatment of FGF2-expressing human multipotent adipose-derived stem cells with PD173074 decreases dramatically their clonogenicity and differentiation potential.
|Handling||Protect from air and light|