PDGFR Tyrosine Kinase Inhibitor V

SKU
P-1689
  • CAS:347155-76-4
  • Formula:C26H23N3O43H2O
  • MW:527.6
  • Appearance:Off-White Solid
  • Purity:95%
Product Name Qty
PDGFR Tyrosine Kinase Inhibitor V
1 mg
$329.19
A cell-permeable quinolinyl-thiourea compound that acts as a potent, ATP-competitive, and reversivle inhibitor of PDGFR. Inhibits c-kit receptor only at much highter concentrations. Shown to potently inhibit neointima formation in a rat carotid artery baloon injury model in vivo.
More Information
SKU
P-1689
CAS #
347155-76-4
Chemical Name
N-(4-((6,7-DIMETHOXY-4-QUINOYL)OXY)PHENYL)-N'-(2-METHYLBENZOYL)THIOUREA
Chemical Formula
C26H23N3O43H2O
Molecular Weight
527.6
Appearance
Off-White Solid
Purity
95%
Solubility
DMSO
Storage Temp
+2°C to +8°C
USE
A cell-permeable quinolinyl-thiourea compound that acts as a potent, ATP-competitive, and reversivle inhibitor of PDGFR
INCHI
InChI=1S/C26H23N3O4S.3H2O/c1-16-6-4-5-7-19(16)25(30)29-26(34)28-17-8-10-18(11-9-17)33-22-12-13-27-21-15-24(32-3)23(31-2)14-20(21)22;;;/h4-15H,1-3H3,(H2,28,29,30,34);3*1H2
SMILES
CC1=CC=CC=C1C(=O)NC(=S)NC2=CC=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC.O.O.O
Handling
Protect from light
Certificate of Analysis 1
HandlingProtect from light
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