Penicillic Acid
SKU
P-1179
- CAS:90-65-3
- Formula:C8H10O4
- MW:170.16 Da
- Appearance:White powder
- Purity:≥98%
SDS
CofA
Antibiotic, Mycotoxin that induces DNA single-strand breaks. Anti-HIV Activity.
More Information
Alternate Name/Synonyms
3-Methoxy-5-methyl-4-oxo-2,5-hexadienoic acid; Penicillinsaure; Kyselina penicilova
SKU
P-1179
CAS #
90-65-3
Chemical Name
3-Methoxy-5-methyl-4-oxo-2,5-hexadienoic acid
Chemical Formula
C8H10O4
Molecular Weight
170.16 Da
Appearance
White powder
Purity
≥98%
Solubility
Soluble in water
Melting Point
83-84°C
Preparation
N/A
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
Penicillic acid is a mycotoxin isolated from various strains of Penicillium and Aspergillus fungi that demonstrates mutagenic and cytotoxic effects. This compound is demonstrated to induce single-strand DNA breaks and to inhibit DNA synthesis in CHO cells. Penicillic acid is also reported to irreversibly inactivate GMD (GDP-mannose dehydrogenase), interrupting the committed step in alginate biosynthesis. Penicillic acid is an inhibitor of ADH/AKR1A1 and LDH.
Merck Index
Merck Index: 13.7163.2001
MDL NUMBER
MFCD00004365
CHEMACX
X1008780-6
INCHI
InChI=1S/C8H10O4/c1-5(2)8(11)6(12-3)4-7(9)10/h4H,1H2,2-3H3,(H,9,10)/b6-4+
SMILES
CC(=C)C(=O)/C(=CC(=O)O)/OC
Peptide sequence
Not Applicable
RTECS
MM2625000
UN #'S
UN 3462
PACKING GROUP
II
HAZARD CLASS
Not Applicable
Handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire protection.
Certificate of Analysis 1
Certificate of Analysis 2
| GHS PICTOGRAMS |
|
|---|---|
| Handling | Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire protection. |
| UN #'S | UN 3462 |
| Packing Group | II |
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