Perifosine

SKU
P-2392
  • CAS:157716-52-4
  • Formula:C25H53NO4P
  • MW:462.66
  • Appearance:White to off-white Solid
  • Purity:99%

0

0

0

0

Product Name Qty
Perifosine
5 mg
$222.12
Perifosine
25 mg
$677.75
Belongs to an alkylphospholipid class of antineoplastic compounds that display potent antiproliferative activity in several in vitro and in vivo human tumor models. Perifosine induces apoptotic cell death in a variety of tumor cell lines. Apoptosis is induced in a time- and dose-dependent manner in U937 and Jurkat T human leukemia cell lines but not in normal vascular endothelial cells.
More Information
Alternate Name/Synonyms
KRX-0402
SKU
P-2392
CAS #
157716-52-4
Chemical Name
1,1-DIMETHYLPIPERIDINIUM-4-YL OCTADECYL PHOSPHATE
Chemical Formula
C25H53NO4P
Molecular Weight
462.66
Appearance
White to off-white Solid
Purity
99%
Solubility
Soluble in H2O (10 mg/ml)
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
An alkylphospholipid which inhibits Akt activation and the anti-apoptotic MAPK pathway used for variety of cancers
MDL NUMBER
MFCD00927554
CHEMACX
X1600392-6
INCHI
InChI=1S/C25H52NO4P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-29-31(27,28)30-25-20-22-26(2,3)23-21-25/h25H,4-24H2,1-3H3/p+1
SMILES
CCCCCCCCCCCCCCCCCCOP(=O)(O)OC1CC[N+](CC1)(C)C
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light and moisture
Handling Protect from light and moisture
UN #'S Not Applicable
Packing Group Not Applicable
To Top