- Formula:C55H85O21N20S2Cu • HCl
- Appearance:Light blue powder
Phleomycin is produced by Streptomyces verticullus and part of the structurally related group of Bleomycin/Phleomycin type antibiotics. Used as a selective agent in transformation experiments with mammalian cells, plant cells and yeast.
Cytotoxic action of this type antibiotic results from the ability to cause fragmentation of DNA. In Vitro studies indicate that Phleomycin causes accumulation of cells in the G2 phase of the cell cycle.
• UV absorbance (244 nm, 600 µg/mL, 0.1 cm path): 0.20 - 0.30
Not for human therapeutic use or for medicinal purposes. For research applications only.
|Handling||Very hygroscopic! Keep container tightly sealed until ready for use. Use in a chemical fume hood, with air supplied by an independent system. Avoid inhalation, contact with eyes, skin and clothing. Avoid the formation of dust and aerosols. Use in a well-ventilated area. Keep away from sources of ignition. Avoid prolonged or repeated exposure.|