Phleomycin, Powder

SKU
P-2853
  • CAS:11006-33-0
  • Formula:C55H85O21N20S2Cu • HCl
  • MW:1525
  • Appearance:Light blue powder
Product Name Qty
Phleomycin, Powder
250 mg
$689.00
Phleomycin, Powder
5 mg
$74.00
Phleomycin, Powder
25 mg
$195.00
Phleomycin, Powder
100 mg
$475.00

Description

Phleomycin is produced by Streptomyces verticullus and part of the structurally related group of Bleomycin/Phleomycin type antibiotics. Used as a selective agent in transformation experiments with mammalian cells, plant cells and yeast.

Cytotoxic action of this type antibiotic results from the ability to cause fragmentation of DNA. In Vitro studies indicate that Phleomycin causes accumulation of cells in the G2 phase of the cell cycle.

 

Specifications

• UV absorbance (244 nm, 600 µg/mL, 0.1 cm path): 0.20 - 0.30

 

Not for human therapeutic use or for medicinal purposes. For research applications only.

More Information
Alternate Name/Synonyms
Phleomycin complex; NSC 61586
SKU
P-2853
CAS #
11006-33-0
Chemical Name
2-[2-[2-[[2-[[4-[[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[(2R,3S,4S,5S,6S)-3-[(2S,3R,4R,5S)-4-carbamoyl-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)-
Chemical Formula
C55H85O21N20S2Cu • HCl
Molecular Weight
1525
Appearance
Light blue powder
Solubility
Water
Storage Temp
2-8°C
THERAPEUTIC AREA
Antibiotic
USE
Selective agent for transformation experiments with mammalian cells, plant cells, and yeast.
Handling
Very hygroscopic! Keep container tightly sealed until ready for use. Use in a chemical fume hood, with air supplied by an independent system. Avoid inhalation, contact with eyes, skin and clothing. Avoid the formation of dust and aerosols. Use in a well-ventilated area. Keep away from sources of ignition. Avoid prolonged or repeated exposure.
Certificate of Analysis 1
GHS PICTOGRAMS
HandlingVery hygroscopic! Keep container tightly sealed until ready for use. Use in a chemical fume hood, with air supplied by an independent system. Avoid inhalation, contact with eyes, skin and clothing. Avoid the formation of dust and aerosols. Use in a well-ventilated area. Keep away from sources of ignition. Avoid prolonged or repeated exposure.
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