SDS
CofA
Cell-permeable. An antipsychotic drug and D2 dopamine receptor antagonist; binds with high affinity to the cloned 5-HT7 receptor. A Stat5 inhibitor; decreases Stat5 tyrosine phosphorylation, but does not affect Bcr-Abl or other tyrosine kinases.
More Information
Alternate Name/Synonyms
1-[1-[4,4-bis(4-Fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
SKU
P-2397
CAS #
2062-78-4
Chemical Name
1-[1-[4,4-bis(4-Fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
Chemical Formula
C28H29F2N3O
Molecular Weight
461.55
Appearance
White Solid
Purity
98% by TLC
Solubility
DMSO (100 mM)
Melting Point
214-218 °C
Storage Temp
2-8°C
THERAPEUTIC AREA
Psychological Disorders
USE
Pimozide is a D2DR inhibitor and antipsychotic which binds with very high affinity and inhibits SR-7
MDL NUMBER
MFCD00055081
CHEMACX
X1004358-8
INCHI
InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)
SMILES
c1ccc2c(c1)[nH]c(=O)n2C3CCN(CC3)CCCC(c4ccc(cc4)F)c5ccc(cc5)F
Peptide sequence
Not Applicable
RTECS
DE1750000
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and light
| GHS PICTOGRAMS |  |
|---|---|
| Handling | Protect from air and light |
| UN #'S | Not Applicable |
| Packing Group | Not Applicable |
