Pimozide

SKU

P-2397

CAS:2062-78-4
Formula:C₂₈H₂₉F₂N₃O
MW:461.55
Appearance:White Solid
Purity:98% by TLC

SDS

CofA

Product Name	Qty
Pimozide 250 mg $290.47
Pimozide 50 mg $74.04

Details

Cell-permeable. An antipsychotic drug and D2 dopamine receptor antagonist; binds with high affinity to the cloned 5-HT7 receptor. A Stat5 inhibitor; decreases Stat5 tyrosine phosphorylation, but does not affect Bcr-Abl or other tyrosine kinases.

Specifications

More Information

Alternate Name/Synonyms

1-[1-[4,4-bis(4-Fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one

SKU

P-2397

CAS #

2062-78-4

Chemical Name

1-[1-[4,4-bis(4-Fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one

Chemical Formula

C₂₈H₂₉F₂N₃O

Molecular Weight

461.55

Appearance

White Solid

Purity

98% by TLC

Solubility

DMSO (100 mM)

Melting Point

214-218 °C

Storage Temp

2-8°C

THERAPEUTIC AREA

Psychological Disorders

USE

Pimozide is a D2DR inhibitor and antipsychotic which binds with very high affinity and inhibits SR-7

MDL NUMBER

MFCD00055081

CHEMACX

X1004358-8

INCHI

InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)

SMILES

c1ccc2c(c1)[nH]c(=O)n2C3CCN(CC3)CCCC(c4ccc(cc4)F)c5ccc(cc5)F

Peptide sequence

Not Applicable

RTECS

DE1750000

UN #'S

Not Applicable

PACKING GROUP

Not Applicable

HAZARD CLASS

Not Applicable