- Formula:C13H19N5 • H2O
- Appearance:White powder
Pinacidil Monohydrate is a potassium channel activator and an anti-hypertensive. It activates ATP-dependent potassium channels. Induces vascular relaxation and antihypertensive effects. Prevents the loss of mitochondrial inner membrane potential, protecting cerebellar granule neurons from apoptosis induced by oxidative stress. Displays protective effects in Parkinson’s disease models and cerebral ischemiareperfusion.
Pinacidil Monohydrate has an important role in Stem Cell Research, it promotes survival of Human Embryonic Stem Cells after cryopreservation.