PP3

SKU
P-2404
  • CAS:5334-30-5
  • Formula:C11H9N5
  • MW:211.22
  • Appearance:Beige Solid
  • Purity:94% by HPLC

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Product Name Qty
PP3
50 mg
$290.47
PP3
10 mg
$74.04
A negative control for the Src family kinase inhibitor PP2 (Cat. No. 1767-1,5). Inhibits the activity of EGFR kinase at an IC.Cooperation between integrin 5 and tetraspan TM4SF5 regulates VEGF-mediated angiogenic activity, Adhesion-dependent Cofilin Serine 3 Phosphorylation by the Integrin-linked Kinase-Src Complex.PKC and cofilin activation affects peripheral actin reorganization and cell-cell contact in cells expressing integrin 5 but not its tailless mutant.
More Information
Alternate Name/Synonyms
4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine; NSC 1401
SKU
P-2404
CAS #
5334-30-5
Chemical Name
4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine; NSC 1401
Chemical Formula
C11H9N5
Molecular Weight
211.22
Appearance
Beige Solid
Purity
94% by HPLC
Solubility
DMSO (100 mM) and EtOH (25 mM)
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
PP 3 is a negative control for the Src family protein tyrosine kinase inhibitor PP2
MDL NUMBER
MFCD00022901
CHEMACX
X1279595-6
INCHI
InChI=1S/C11H9N5/c12-10-9-6-15-16(11(9)14-7-13-10)8-4-2-1-3-5-8/h1-7H,(H2,12,13,14)
SMILES
c1ccc(cc1)n2c3c(cn2)c(ncn3)N
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and light
Citations
RESEARCH ARTICLES: PKC and cofilin activation affects peripheral actin reorganization and cell-cell contact in cells expressing integrin 5 but not its tailless mutant Min-A Oh, Eun-Sil Kang, Sin-Ae Lee, Eun-Ok Lee, Yong-Bae Kim, Sung-Hoon Kim, and Jung Weon Lee J. Cell Sci., Aug 2007; 120: 2717 - 2730.
Citations_Hyperlink
http://jcs.biologists.org/cgi/reprint/120/15/2717
Certificate of Analysis 1
GHS PICTOGRAMS
Handling Protect from air and light
UN #'S Not Applicable
Packing Group Not Applicable
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