Pravastatin sodium

SKU
P-2787
  • CAS:81131-70-6
  • Formula:C23H35O7Na
  • MW:446.5
  • Appearance:White powder
  • Purity:>98% by HPLC
Product Name Qty
Pravastatin sodium
25 mg
$113.02
Pravastatin sodium
100 mg
$396.19
*Please inquire the availability for this product. Pravastatin sodium is the salt of pravastatin, a ring-opened member of the statin family. Pravastatin is produced biosynthetically from compactin (mevastatin) by a number of microorganisms, notably Absidia, Cunninghamella, Syncephalastrum, Nocardia or Streptomyces. Typically, statins like compactin, lovastatin and simvastatin possess a β-hydroxy lactone ring which is a pro-drug for the readily ring-opened dihydroxyacid generally regarded as the active HMG-CoA reductase inhibitor. Importantly, the free carboxylic acid enables pravastatin to be freely water soluble within biological pH ranges.
More Information
Alternate Name/Synonyms
Mevalotin, CS 514, SQ 3100
SKU
P-2787
CAS #
81131-70-6
Chemical Formula
C23H35O7Na
Molecular Weight
446.5
Appearance
White powder
Purity
>98% by HPLC
Solubility
Soluble in water
Melting Point
171.2-173 °C
Storage Temp
4°C
THERAPEUTIC AREA
Metabolic Disorders
USE
Pravastatin Sodium is a competitive HMGCR (HMG-CoA reductase) inhibitor that potently blocks cholesterol synthesis
MDL NUMBER
MFCD00887601
INCHI
InChI=1S/C23H36O7.Na/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28;/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28);/q;+1/p-1/t13-,14-,16+,17+,18+,19-,20-,22-;/m0./s1
SMILES
CC[C@H](C)C(=O)O[C@H]1C[C@@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)[O-])O)O)O.[Na+]
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