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A23187, Free Acid, 25 MG

Price$ 267.00
  • SKU: A-1020-25MG
  • Pack Size: 25 MG

Frequently Bought Together

Total price: $ 361.75

This item: A23187, Free Acid, 25 MG $ 267.00

A23187, Free Acid, 5 MG $ 94.75

Calcium ionophore A23187; Calcimycin




DMSO, Methanol, Dicholormethane


A23187, Free Acid is a carboxylic acid antibiotic derived from cultures of Streptomyces chartreusensis that transports divalent cations across cell membranes, which are usually impermeable to them. This mobile Ion - carrier  forms stable complexes with divalent cations (ions with a charge of +2).


The ionophore is used in laboratories to increase intracellular Ca2+ levels in intact cells. A23187 has antibiotic properties against Gram-positive bacteria and fungi.  A23187 also induces apoptosis in some cells (e.g. mouse lymphoma cell line, or S49, and Jurkat cells). Recent clinical studies indicate that treatment of oocytes lacking a 2ndPb with A23187 at 4.5–5.0 h after ICSI (Intracytoplasmic sperm injection) is expected to be effective at preventing fertilization failure.


0.1 lbs

Research or further manufacturing use only, not for food or drug use.

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