Quick Order Pad
Your Shopping Cart is Empty
Hello, Sign In

A23187, Free Acid, 50 MG

Price$ 742.50
  • SKU: A-1020-50MG
  • Pack Size: 50 MG
Quantity
-
+

Calcium ionophore A23187; Calcimycin

52665-69-7

523.63

C29H37N3O6

DMSO, Methanol, Dicholormethane

-20°C


A23187, Free Acid is a carboxylic acid antibiotic derived from cultures of Streptomyces chartreusensis that transports divalent cations across cell membranes, which are usually impermeable to them. This mobile Ion - carrier  forms stable complexes with divalent cations (ions with a charge of +2).

 

The ionophore is used in laboratories to increase intracellular Ca2+ levels in intact cells. A23187 has antibiotic properties against Gram-positive bacteria and fungi.  A23187 also induces apoptosis in some cells (e.g. mouse lymphoma cell line, or S49, and Jurkat cells). Recent clinical studies indicate that treatment of oocytes lacking a 2ndPb with A23187 at 4.5–5.0 h after ICSI (Intracytoplasmic sperm injection) is expected to be effective at preventing fertilization failure.


 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

Product Recommendations