1397-89-3
924.091 Da
C47H73NO17
DMSO (35 mg/ml), DMF (3 mg/ml), water (no information available)
+4°C
Synonym: (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,
Description
Amphotericin B is a polyene anti-fungal antibiotic from Streptomyces nodosus that non-specifically induces loss of low molecular weight substances from cells. It binds to sterols and disrupts osmotic integrity of fungal membranes, forming pores which leads to the leakage of essential ions, causing cell death.
Applications
• Amphotericin B is used to control contamination from fungi, viruses, and protozoa.
• Treatment of serious, life-threatening fungal infections. Not to be used for treatment of minor fungal infections.
Specifications
• Beilstein Registry Number: 78342
• EC Number: 215-742-2
Additional Reading from AG Scientific
• Amphotericin B for Viral Research
• Polyene Macrolide Antibiotics
• A Guide to the 8 Most Common Classes of Antibiotics
• What Can Be Done to Fight Antibiotic Resistance?
• Download Brochure: Antibiotics
Reference
• "Virtual screening of an FDA approved drugs database on two COVID-19 coronavirus proteins"
Not for human therapeutic use or for medicinal purposes. For research applications only.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
