[(2R,3S,4S)-4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl] acetate

Description

Anisomycin is isolated from several species of Streptomyces griseolus. It interferes with the synthesis of protein and DNA by inhibiting the peptidyl transferase of the 80S ribosomal system. Anisomycin is also a JNK agonist, MAP kinases activator, anti-protozoal agent, and an apoptosis promoter in promyelocytic leukemia cells, Jurkat cells, ventricular monocytes, and colon adenocarcinoma cells.

 

Applications

• antibacterial, for its ability to reduce growth and block the diffusion of bacteria
• antiprotozoal, for its effectiveness in the destruction of protozoa
• Inhibitor of nucleic acid and protein synthesis

 

Additional Reading: Popular Anti-Fungal Drugs

 

Not for human therapeutic use or for medicinal purposes. For research applications only.