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Bacimethrin, 500 UG

Price$ 150.76
  • SKU: B-2396-500UG
  • Pack Size: 500 UG



Soluble in DMSO or methanol


Bacimethrin is isolated from Streptomyces albus. Bacimethrin is toxic to bacteria(e.g. B.cereus, E.coli and Proteus vulgaris) and yeast(e.g. Saccharomyces cerevisiae 7156, Cryplococcus neoformans and C. lauretii) growing in minimal media and has a minimum inhibitory concentration(MIC) in the low micromolar range. The toxicity can be reversed by adding thiamin to the culture medium.

Bacimethrin is inactive against sarcoma 180, leukaemia L-1210, sarcoma 37 and Ehrlich carcinoma, nor is it active against Newcastle disease virus and HeLa cells, or against T2 phage of E.coli B2.

Bacimethrin is a substrate for the thiamin biosynthetic enzymes. It is an analog of the 4-amino-5-hydroxymethyl-2-methylpyrimidine(HMP) moiety of thiamine and inhibits the growth of Salmonella enterica.

The structure of bacimethrin is remarkably similar to those of 5-(hydroxy-methyl)cytosine and Bayer DG-428646-648.The structural resemblance to vitamins B1 and B6 probably explains the fact that the antibiotic activity of bacimethrin is antagonized by vitamins B1 and B6.


0.1 lbs

Research or further manufacturing use only, not for food or drug use.