C59H84N2O18 (for Candicidin D)
Poorly soluble in most organic solvents. Soluble in tetrahydrofuran 80% aqueous.
Candicidin is a macrocyclic heptaene antifungal complex produced by Streptomyces griseus and isolated by Lechevalier and colleagues in 1953. The candicidin complex comprises analogues A, B, C and D, with candicidin D as the major component. Candicidin is active against fungi, in particular Candida albicans, and is used clinically to treat vaginal candidiasis. Like all polyene antifungal metabolites, candicidin acts by binding to ergosterol and disrupting the fungal membrane.
Research or further manufacturing use only, not for food or drug use.