4800-94-6
422.4
C17H16N2O6SNa2
Soluble in water: clear and slightly yellow solution at 50 mg/mL
+4°C
Description
Carbenicillin Disodium Salt is a penicillin-derived β-lactam antibiotic that interferes with cell wall synthesis, primarily in gram-negative bacteria such as Pseudomonas aeruginosa, while showing low toxicity to plant tissues. Carbenicillin acylates the penicillin-sensitive transpeptidase C-terminal area by opening the lactam ring. This inactivation intercepts the cross-linkage of peptidoglycan strands, by impeding the third and last phase of bacterial cell wall synthesis. This prompts inadequate bacterial cell wall synthesis and causes cell lysis.
Applications
• Used in selection protocols over ampicillin due to its increased stability
• Used in genetic transformation applications to select for AmpR transformed cells
• Used to regulate bacterial growth in plants, yielding low regeneration frequencies
• Used as a gene selection antibiotic in plant biology utilizing the CRISPR/CAS9 system
Not for human therapeutic use or for medicinal purposes. For research applications only.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
