Cefotaxim sodium salt
Cefotaxime sodium salt is a potent cephalosporin antibiotic that inhibits bacterial cell wall synthesis by binding to PBPs (penicillin-binding proteins). This binding action inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls, resulting in lysis of bacteria. Cefotaxime was discovered in 1976 and is now listed on the World Health Organization's List of Essential Medicines.
Cefotaxime sodium salt is effective against both Gram-negative and Gram-positive bacteria and is resistant to β -lactamase. Cefotaxime also prevents division of cyanobacteria and lower plant organelles such as the photosynthetic components of Glaucophtyes and the chloroplasts of bryophytes.
Cefotaxime has been used to treat joint infections, inflammatory diseases, meningitis, pneumonia, sepsis, urinary tract infections, gonorrhea, and cellulitis.
- EC Number: 264-915-9
- Antibiotic Activity Spectrum: Gram-negative and Gram-positive bacteria
- Mode of Action: Interferes with cell wall synthesis
Research or further manufacturing use only, not for food or drug use.