Quick Order Pad
Your Shopping Cart is Empty
Hello, Sign In

CJ-21058, 1 MG

Price$ 108.55
  • SKU: C-2398-1MG
  • Pack Size: 1 MG
Quantity
-
+

405072-57-3

387.5

C23H33NO4

Soluble in methylene chloride, DMSO or methanol

-20°C


CJ-21058 isolated from Phoma sp. is a close analog of equisetin, a fungal toxin.

Equisetin differs only in having a hydrogen atom at C-4 position of CJ-21058. It is also known to show a broad range of biological activites such as antibacterial, anti-HIV, cytotoxicity and DNA binding properties. The striking structural similarities between CJ-21058 and qeuisetin as well as their potent antibacterial properties point towards a possible correlation between antibacterial and SecA inhibitory activities of these compounds.

CJ-21058 shows antibacterial activity against gram-positive multi-drug resistant bacteria such as Staphylococcus aureus and Enterococcus faecalis(MIC=5µg/ml) by inhibiting ATP-dependent translocation of precursor proteins across a bacterial cell membrane. But it has no activity against Streptococcus pyogenes and Escherichia coli

 

Product References

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

Product Recommendations