Actidione; Naramycin A; Kaken; Hizarocin; Zykloheximid; Neocycloheximide
Cycloheximide is an antibiotic produced by Streptomyces sp. that activates against yeasts and fungi. It inhibits protein synthesis thru DNA translation arrest in eukaryotes. Cycloheximide also inhibits chain initiation and chain elongation by acting on 60S subunits of eukaryote ribosome.
- Used as an inhibitor to study cell-free protein biosynthesis in eukaryotes
- Used to block ribosome-dependent in vivo polypeptide synthesis
- Used in genome editing utilizing the CRISPR/Cas9 system
- Used to clear macrophages in atherosclerotic plaques
- Used to activate cumulus-free equine oocytes, and to have neuroprotective properties
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Research or further manufacturing use only, not for food or drug use.