Soluble inDMSO (25 mg/mL), methanol, 100% ethanol (25 mg/mL), or acetone. Insoluble in water.
Potent immunosuppressor. Inhibitor of the mitochondrial permeability transition pore (MPTP), preventing necrosis in several models. Isolated from Fusarium solani. Mitochondria are the primary target in isothiocyanate-induced apoptosis in human bladder cancer cells. The Influence of B-Cell Lymphoma 2 Protein, an Antiapoptotic Regulator of Mitochondrial Permeability Transition, on Isoflurane-Induced and Ischemic Postconditioning in Rabbits.Delineating the mechanism by which selenium deactivates Akt in prostate cancer cells.
Research or further manufacturing use only, not for food or drug use.