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Cytochalasin B, Helminthosporium dematioideum, 5 MG

Price$ 151.18
  • SKU: C-1027-5MG
  • Pack Size: 5 MG
Quantity
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+

14930-96-2

479.6 Da

C29H37NO5

Soluble in DMSO or Ethanol.

-20°C


Description

Cytochalasin B is a heterotricyclic compound that acts as a mycotoxin. Cytochalasin B inhibits cytokinesis during cell division by preventing microfilament formation. While preventing cytokinesis from occurring, this compound exerts no effect on the division of the nucleus. Cytochalasin B also inhibits several processes within cells, including both the formation of actin filaments and the normal transport of glucose. Cytochalasin B acts as a microtubule inhibitor isolated from Helminthosporium dematioideum.

Applications

Owing to its ability to permeate cells and inhibit several aspects of their ordinary activity, cytochalasin B has been used widely in cytological research to investigate cellular processes. Along with the other cytochalasins, this compound has also been studied as a potential anticancer drug. In both in vitro and in vivo studies, cytochalasins have been shown to damage cancerous cells to a greater extent than non-cancerous cells. Another line of investigation into cytochalasin B's in vivo effects has focused on its ability to restore elasticity to the skin cells of mice by impeding f-actin polymerization. Cytochalasin B also induces cellular DNA Fragmentation.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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