Soluble in water
Ertapenem is a new carbapenem which has β-Lactam features and is regarded as having the most potent and the widest spectrum of antimicrobial activity, like imipenem and meropenem. It is effective against both Gram-negative and Gram-positive aerobes and anaerobes and is resistant to nearly all beta-lactamases, including extended-spectrum Beta-lactamases and AmpCs.
Ertapenem has a mechanism that suppresses synthesis of bacterial cell walls. The drug binds to penicillin binding proteins (PBPs), especially PBPs 2 and 3, on bacterial cell walls and inhibits the synthesis of peptidoglycan by interfering the final transpeptidation step.
This antibiotic is approved in the US and the EU as a parenteral infection treatment. It is used for intra-abdominal infection, complicated skin and soft-tissue infections, community-acquired pneumonia and acute pelvic infection.
• Used to treat inflammatory diseases
Not for human therapeutic use or for medicinal purposes. For research applications only.
Research or further manufacturing use only, not for food or drug use.