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Fidaxomicin, 50 MG

Price$ 82.80
  • SKU: F-2425-50MG
  • Pack Size: 50 MG
Quantity
-
+

873857-62-6

1,058

C52H74Cl2O18

Clear colorless solution at 1mg/ml of DMSO; Clear colorless solution at 5 mg/ml of Methanol

-20°C


Description

Fidaxomicin is a recently marketed antibiotic with a confusing history dating back to its original isolation in 1975. Fidaxomicin is the major analogue of a family of macrocyclic lactones, isolated independently by three different groups from cultures belonging to three different genera (Actinoplanes, Dactylosporangium and Micromonospora) known as lipiarmycin A3, tiacumicin B and clostomicin B1, respectively. Fidaxomicin is a narrow spectrum antibiotic with excellent activity against Gram-positive bacteria, notably Clostridium difficile. Fidaxomicin acts in the gastrointestinal tract without undue disruption to gut microflora.

Fidaxomicin is used to treat diarrhea caused by Clostridium difficile.

Isolated from Dactylosporangium aurantiacum.

Additional reading: Fidaxomicin Applications

 

References

• Antibiotic fidaxomicin is an RdRp inhibitor as a potential new therapeutic agent against Zika virus

• Synthesis and Biological Evaluation of Iodinated Fidaxomicin Antibiotics

• First-line Fidaxomicin Use in High-risk Inpatients Reduces Recurrence Rates

• Fidaxomicin for the treatment of Clostridioides difficile in children

• Inhibitory effect of fidaxomicin on biofilm formation in Clostridioides difficile

 

Not for human therapeutic use or for medicinal purposes. For research applications only.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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