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Fumagillin, 1 MG

Price$ 54.93
  • SKU: F-1028-1MG
  • Pack Size: 1 MG


458.6 Da


Dissolve in DMSO (25mg/ml) or Methanol (5mg/ml)



Fumagillin is used as an antimicrobial agent from Aspergillus fumigatus. It is a specific inhibitor of methionine aminopeptidase-2 (MetAP-2) by covalently binding histidine residue of it. It is reported that this fungal metabolite suppresses angiogenesis and proliferation of endothelial cells.

It is a potent treatment of intestinal microsporidiosis in immunocompromised patients. It is reported that a derivative of fumagillin, AGM-1470, is related to angioinhibitory action by suppressing of mRNA expression of specific members of CDKs and cyclins and activation of CDC2 and CDK2 kinases in endothelial cells.



• Antimicrobial agent

• Study for anticancer agent



• “Fumagillin Treatment of Intestinal Microsporidiosis”

• “Fumagillin Derivative Angiogenesis Inhibitor, AGM-1470, Inhibits Activation of Cyclin-dependent Kinases and Phosphorylation of Retinoblastoma Gene Product but not Protein Tyrosyl Phosphorylation or Protooncogene Expression in Vascular Endothelial Cells”


Not for human therapeutic use or for medicinal purposes. For research applications only.

0.1 lbs

Research or further manufacturing use only, not for food or drug use.

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