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G-418 Sulfate, 25 G

Price$ 395.00
You Save$ 855.00
  • SKU: G-1033-25GM
  • Pack Size: 25 G
Quantity
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Frequently Bought Together

Total price: $ 1,888.00

This item: G-418 Sulfate, 25 G $ 395.00

G-418 Sulfate, 100 G $ 1,250.00

Bongkrekic Acid, 100 UG $ 243.00

108321-42-2

692.7 Da

C20H40O10N4 • 2H2SO4

Soluble in water: 100mg/ml, colorless solution

+4°C


Description

G-418 Sulfate Salt (Geneticin) is an aminoglycoside antibiotic that is synthesized from Micromonospora rhodorangea and functions by causing a chain of nonsense mutations during translation. Due to translation G-418 inhibited polypeptide synthesis and protein elongation. G-418 binds to the 80S subunit of the ribosome by blocking the elongation phase of protein synthesis, both in prokaryotic and eukaryotic cells. It also shows activity against protozoa, cecal amoebiasis, and helminthes.

 

Applications:

• Used routinely in molecular genetics experiments for selecting eukaryotic transformants
• Used in plant and mammalian cell culture as a selectable marker
• Used as a gene selection antibiotic that has a powerful new role in genome editing, utilizing the CRISPR/CAS9 system.
• Ability to inhibit poliovirus and rhinovirus 2A proteinases in vitro

 

Not for human therapeutic use or for medicinal purposes. For research applications only.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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