158792-27-9
1132.1
C50H49N15O15S
Soluble in methanol, DMF, DMSO, and ethanol
+4°C
*Please inquire the availability for this product. Geninthiocin, a thiopeptide antibiotic isolated from a Streptomyces sp., is a potent activator of the tipA gene, a bacterial transcription regulator involved in multidrug resistance. Geninthiocin displays a 10-fold selectivity for bacteria over mammalian cells lines, whereas the related dedialanyl geninthiocin shows the reverse selectivity. Geninthiocin is closely related to siomycin, a recently discovered inhibitor of oncogenic transcription factor, FoxM1.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
