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Hygromycin B in PBS Buffer, 1X1 G (1X20 mL)

Price$ 109.73
You Save$ 12.04
  • SKU: H-1012-PBS-1GM (1X20ML)
  • Pack Size: 1X1 G (1X20 ML)
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Total price: $ 356.36

This item: Hygromycin B in PBS Buffer, 1X1 G (1X20 mL) $ 109.73

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31282-04-09

527.5 Da

C20H37N3O13

Soluble in water

2-8°C


* The concentration of Hygromycin B in PBS buffer is 50 mg/ml 

Description

Hygromycin B is an aminoglycoside antibiotic isolated from Streptomyces hygroscopicus. It is commonly used to study protein synthesis. Aside from its efficacy against bacteria, fungi, and higher eukaryotic cells, hygromycin B is also an antiviral agent inhibiting translation upon selectively entering cells made permeable due to viral infection. It works as a standard selection antibiotic in gene experiments, especially for selection of hygromycin resistance gene transformed cells.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. Hygromycin's longstanding application as a gene selection antibiotic, has a powerful new role in genome editing utilizing the CRISPR/CAS9 system.

 

Additional Reading

• Hygromycin B: Frequently Asked Questions

 

* ATTENTION! International shipping of this material can be subject to an additional hazardous shipping fee. An AG Scientific customer service representative will contact you to confirm cost prior to shipping your international order. 

 

Not for human therapeutic use or for medicinal purposes. For research applications only.

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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