Kanamycin monosulfate; Kanamycin; Kanamycin A; Kanamycin Sulfate Salt; Kanamycin acid sulfate
C18H36N4O11 • H2SO4
Kanamycin is an aminoglycosidic antibiotic that inhibits growth of gram-positive, gram-negative bacteria and mycoplasmas in cell culture. Kanamycin or kanamycin A is a major component of the antibiotic complex produced by certain strains of Streptomyces kanamyceticus.
Kanamycin is supplied in two forms, a crystalline monosulfate monohydrate and a salt with a higher sulfate content. Kanamycin sulfate, which is sometimes referred to as “kanamycin bisulfate,” is obtained by adding sulfuric acid to a solution of the monosulfate and drying using a suitable procedure. Kanamycin sulfate binds to 30S ribosomes causing inhibition of bacterial protein synthesis.
- Laboratory Use - resistance marker to grow plasmids of interest in competent bacterial cells.
- Therapeutic Use - a second-line anti-tuberculosis drug.
Research or further manufacturing use only, not for food or drug use.