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Nimbolide, 5 MG

Price$ 235.18
  • SKU: N-2365-5MG
  • Pack Size: 5 MG
Quantity
-
+

25990-37-8

466.52

C27H30O7

DMSO (50 mM)

-20°C


A terpenoid lactone derived from Azadirachta indica (Neem tree) that displays a variety of biological activities including anti-malarial and anticancer activity. Recently it has also been shown that nimbolide sensitizes colon cancer cells to TRAIL-induced apoptosis through three distinct mechanisms: reactive oxygen species and ERK-mediated up-regulation of DR5 and DR4, downregulation of cell survival proteins, and up-regulation of pro-apoptotic proteins p53 and Bax.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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