C23H45N5O14 • H2SO4
Paromomycin sulfate is an aminoglycoside antibiotic effective against Gram-negative and Gram-positive bacteria, protozoa and cestodes. The antibiotic has a similar effect as neomycin.
Paromomycin binds to a highly conserved sequence, the A site, of the 16S rRNA of the 30S ribosomal subunit in bacteria. It induces a conformational change and thus interrupts translation and synthesis of protein and leads to cell death.
It has antiprotozoal properties and treats parasitic diseases such as Leishmaniasis.
• Aminoglycoside antibiotic
• Protein synthesis inhibitor
• Selective agent of oat transformation
• Assay: ≥ 675 U/mg
• Loss on Drying: ≤ 5.0%
• pH 3.0% Solution at 25°C: 5.0 - 7.5
• Specific Optical Rotation: +50.0 - +55.0°C
Not for human therapeutic use or for medicinal purposes. For research applications only.
Research or further manufacturing use only, not for food or drug use.